Category C—May be less safe than than other SSRIs. Associated with cardiac malformations with high-dose, first-trimester use (other studies failed to replicate)
RID 0.5-2.8%; ∅AE's have been reported for majority of paroxetine-exposed infants
↓ clearance in the elderly; lower starting dose is recommended
Significantly affected by severe renal disease (CrCl < 30 ml/min), 4-fold ↑'s in plasma concentrations have been reported
Initial dosage should be reduced in patients with severe hepatic impairment
Developed & Designed by Kevin M. Nasky, D.O. • Built with Bootstrap, PHP & MySQL • Hosted by SiteGround
Last updated August 16 2023 14:43:53. Disclaimer: This website does not provide medical advice, nor is it a substitute for clinical judgment.