Category C—∅ studies of zaleplon in pregnant women ∴ not recommended for use during pregnancy
RID 1.5%; Probably safe. Levels in milk averaged 14 ug/liter
Start at 5mg qhs
2019 BEE℞S Recommendation: Avoid. Nonbenzodiazepine benzodiazepine receptor agonist hypnotics (ie, Z drugs) have adverse events similar to those of benzodiazepines in older adults (eg, delirium, falls, fractures); increased emergency room visits/ hospitalizations; motor vehicle crashes; minimal improvement in sleep latency and duration.
No dosage adjustment necessary
Cut dose in half in hepatic insufficiency
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Last updated August 15 2022 20:48:12. Disclaimer: This website does not provide medical advice, nor is it a substitute for clinical judgment.