Category C—Crosses the placenta. No studies in pregnant women.
RID 4.7-19.1%; ∅ AE's have been reported in exposed infants
Start at 5mg to ↓ chances of motor and/or cognitive impairment
2019 BEE℞S Recommendation: Avoid. Nonbenzodiazepine benzodiazepine receptor agonist hypnotics (ie, Z drugs) have adverse events similar to those of benzodiazepines in older adults (eg, delirium, falls, fractures); increased emergency room visits/ hospitalizations; motor vehicle crashes; minimal improvement in sleep latency and duration.
No dosage adjustment necessary.
↓ dose to 5 mg qhs for hepatically impaired
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Last updated March 25 2019 15:25:58. Disclaimer: This website does not provide medical advice, nor is it a substitute for clinical judgment.