Category Not assigned.—There are no available data on VRAYLAR use in pregnant women to inform any drug-associated risks for birth defects or miscarriage.
It is not known if cariprazine is excreted in breast milk.
All atypicals may increase mortality in elderly patients by 1.7 times greater than placebo.
2019 BEE℞S Recommendation: Avoid, except in schizophrenia or bipolar disorder. Increased risk of CVA and greater rate of cognitive decline and mortality in persons with dementia. Avoid antipsychotics for behavioral problems of dementia or delirium unless nonpharmacological options have failed or are not possible and the older adult is threatening substantial harm to self or others.
No dosage adjustment necessary
Mild to moderate impairment: No dosage adjustment necessary; Severe impairment: Use not recommended
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Last updated March 25 2019 15:25:58. Disclaimer: This website does not provide medical advice, nor is it a substitute for clinical judgment.