Category C—Majority of data based on illicit amphetamine and methamphetamine use. May increase risk for premature birth and low birth weight. Newborns may experience withdrawal. Children may experience behavioral problems.
Majority of data based on illicit amphetamine and methamphetamine use. Amphetamine are excreted into breast milk in higher concentrations than present in mothers serum. May decrease milk production. Can cause irritability, agitation, and crying in nursing infants.
Start lower, i.e. 10 mg/d (typical dose is 20 mg/d); consider a 5 mg/d starting dosage for especially frail patients; give second dose mid-afternoon to avoid insomnia
No adjustments necessary
No dosage adjustments necessary