Category Undefined.—Both quinidine & DXM are considered to be compatible with pregnancy
DXM is considered to be compatible with breastfeeding; the American Academy of Pediatrics has classified quinidine as compatible with breastfeeding
The pharmacokinetics of dextromethorphan/quinidine have not been investigated systematically in elderly subjects
Dose adjustment is not required in mild or moderate renal impairment. Has not been studied in patients with severe renal impairment.
Mild to moderate hepatic impairment had little effect on quinidine pharmacokinetics. Neither dextromethorphan alone nor NUEDEXTA has been evaluated in patients with severe hepatic impairment.