Category C—GDM may be a problem with all SGAs; may cause extrapyramidal and/or withdrawal symptoms in neonates with third trimester exposure
It is not known if iloperidone is excreted in breast milk. Breast-feeding is not recommended by the manufacturer.
All atypicals may increase mortality in elderly patients by 1.7 times greater than placebo; caution in elderly due to its strong α1 activity and orthostasis and associated fall risk
There are no dosage adjustments required
Mild-moderate impairment: No dosage adjustment necessary. Severe hepatic impairment: Use is not recommended.