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Type a Drug Name. Get the information you're looking for. It's that easy.

Psychopharmacology Database

Psychiatric Drug Reference is a progressive web application aimed at providing clinicians with fast access to psychiatric drug information.

Quickly find indications (including off-label), dosing, side effects, clinically useful pharmacokinetic and pharmacodynamic information, drug-drug interactions, and prescribing pearls for special populations i.e. pregnant, lactating, patients with renal or hepatic impairment, elderly, etc. At last, a virtual Rolodex of psychopharm information, accessible anywhere and across devices.

105 Drugs So Far!

This site is being updated almost daily. Brexanolone is our most recent addition to the rapidly growing drug database.

Drug Tables

Search for Drugs by Mechanism of Action or Diagnosis

We now offer three separate tables in addition to the search bar, two sorted by mechanism of action (brand and generic), and a third new table organized by diagnoses (FDA-indicated and "off-label").

QT/QTc Quick Info

Concerned about QT prolongation when prescribing psychiatric medications?

Check out our new QT reference page with tables summarizing QT prolongation risk factors, including medication tables for both psych and non-psych meds (with comparison of high vs low risk of QT prolongation of various classes of psych meds).

Psychopharm Trivia

Clomipramine, the last of the major TCAs to come to market, was considered to be the most powerful antidepressant ever made. Initially, the FDA regarded it as another 'me-too' drug, and accordingly, they did not license it. Subsequently, however, it was licensed for the treatment of obsessive-compulsive disorders.

From Foye's Principles of Medicinal Chemistry

Cytochrome P450 Table

Preventing Drug-Drug Interactions

All drugs in the psychopharm database populate our CYP450 table, organized into substrates, inhibitors, and inducers of the major CYP pathways (1A2, 2D6, 2C9/C19, 3A4).

Dose Conversion Calculators
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Side-by-side comparison of benzodiazepines

Converting a patient from one benzodiazepine to another? This benzodiazepine conversion tool shows the equipotent dose of the drug you're converting to, while comparing basic pharmacokinetic and prescribing information side-by-side.

Dose Conversion Calculators

Antipsychotic Conversion & Cross-Taper New

The antipsychotic conversion tool allows for quick calculation of equipotent antipsychotic doses for 20 different antipsychotic medications based on published chlorpromazine equivalents and provides suggested cross-taper schedule for making the switch!

Dose Conversion Calculators

Stimulant Conversion Calculator Beta

The stimulant dose conversion calculator is still in progress, and so far can convert doses to/from among Ritalin, Adderall, Vyvanse, Dexadrine, and Focalin. Look for updates to this conversion tool soon!

JAMA Psychiatry's Most Viewed

Genetic and Environmental Associations With Autism in a 5-Country Cohort
Posted on Tuesday July 16, 2019

This population-based cohort study uses national registry data from 5 countries to investigate additive genetic, maternal, and environmental effects on autism spectrum disorder diagnosis.

Is It Time to Ban the P Value?
Posted on Tuesday August 06, 2019

This Viewpoint describes the debate over the misuse of the P value in medical research and advocates adopting modified usage to ensure results are clearly communicated, preferably with an a priori hypothesis and interpretable effect sizes with estimates of accuracy.

What to Tell a Parent Who Worries a Young Child Has Autism
Posted on Tuesday August 06, 2019

This article summarizes evidence for diagnosis of autism spectrum disorder in young children.

Disruptive Psychopharmacology
Posted on Wednesday July 31, 2019

This Viewpoint discusses the potential therapeutic utility of methylenedioxy-methamphetamine and psilocybin and outlines mental health care infrastructures that would need to be put in place should these drugs be approved for treatment.

Esketamine Nasal Spray Plus Oral Antidepressant Treatment in Patients With Treatment-Resistant Depression
Posted on Tuesday June 04, 2019

This randomized withdrawal study compares the efficacy of esketamine nasal spray plus an oral antidepressant with an oral antidepressant plus placebo nasal spray in delaying relapse of depressive symptoms in patients with treatment-resistant depression who were in stable remission after treatment with esketamine nasal spray plus an oral antidepressant.


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Last updated August 08 2019 14:18:39. Disclaimer: This website does not provide medical advice, nor is it a substitute for clinical judgment.