Card image cap

Type a Drug Name. Get the information you're looking for. It's that easy.

Psychopharmacology Database

Psychiatric Drug Reference is a progressive web application aimed at providing clinicians with fast access to psychiatric drug information.

Quickly find indications (including off-label), dosing, side effects, clinically useful pharmacokinetic and pharmacodynamic information, drug-drug interactions, and prescribing pearls for special populations i.e. pregnant, lactating, patients with renal or hepatic impairment, elderly, etc. At last, a virtual Rolodex of psychopharm information, accessible anywhere and across devices.

105 Drugs So Far!

This site is being updated almost daily. Brexanolone is our most recent addition to the rapidly growing drug database.

Drug Tables

Search for Drugs by Mechanism of Action or Diagnosis

We now offer three separate tables in addition to the search bar, two sorted by mechanism of action (brand and generic), and a third new table organized by diagnoses (FDA-indicated and "off-label").

QT/QTc Quick Info

Concerned about QT prolongation when prescribing psychiatric medications?

Check out our new QT reference page with tables summarizing QT prolongation risk factors, including medication tables for both psych and non-psych meds (with comparison of high vs low risk of QT prolongation of various classes of psych meds).

Top 10 searched drugs since launching in Marcb 2017!
Top 10

2.aripiprazole 1127
3.sertraline 1040
4.fluoxetine 875
5.escitalopram 847
6.bupropion 766
7.quetiapine 739
8.mirtazapine 706
9.Depakote 688
10.lurasidone 605

Psychopharm Trivia

Paul Janssen's observation of amphetamine-intoxicated Belgian cyclists gave him the idea to test haloperidol on amphetamine-intoxicated mice, thinking 'finding a treatment for amphetamine intoxication would provide a cure for paranoid schizophrenia.'

Cytochrome P450 Table

Preventing Drug-Drug Interactions

All drugs in the psychopharm database populate our CYP450 table, organized into substrates, inhibitors, and inducers of the major CYP pathways (1A2, 2D6, 2C9/C19, 3A4).

Dose Conversion Calculators
Card image cap

Side-by-side comparison of benzodiazepines

Converting a patient from one benzodiazepine to another? This benzodiazepine conversion tool shows the equipotent dose of the drug you're converting to, while comparing basic pharmacokinetic and prescribing information side-by-side.

Dose Conversion Calculators

Antipsychotic Conversion & Cross-Taper New

The antipsychotic conversion tool allows for quick calculation of equipotent antipsychotic doses for 20 different antipsychotic medications based on published chlorpromazine equivalents and provides suggested cross-taper schedule for making the switch!

Dose Conversion Calculators

Stimulant Conversion Calculator Beta

The stimulant dose conversion calculator is still in progress, and so far can convert doses to/from among Ritalin, Adderall, Vyvanse, Dexadrine, and Focalin. Look for updates to this conversion tool soon!

JAMA Psychiatry's Most Viewed

Genetic and Environmental Associations With Autism in a 5-Country Cohort
Posted on Tuesday July 16, 2019

This population-based cohort study uses national registry data from 5 countries to investigate additive genetic, maternal, and environmental effects on autism spectrum disorder diagnosis.

Disruptive Psychopharmacology
Posted on Tuesday June 25, 2019

This Viewpoint discusses the potential therapeutic utility of methylenedioxy-methamphetamine and psilocybin and outlines mental health care infrastructures that would need to be put in place should these drugs be approved for treatment.

Esketamine Nasal Spray Plus Oral Antidepressant Treatment in Patients With Treatment-Resistant Depression
Posted on Tuesday June 04, 2019

This randomized withdrawal study compares the efficacy of esketamine nasal spray plus an oral antidepressant with an oral antidepressant plus placebo nasal spray in delaying relapse of depressive symptoms in patients with treatment-resistant depression who were in stable remission after treatment with esketamine nasal spray plus an oral antidepressant.

Imaging Study of Cannabinoid 1 Receptor Levels in First-Episode Psychosis
Posted on Tuesday July 02, 2019

This cross-sectional case-control cohort study investigates availability of cannabinoid 1 receptor in patients with first-episode psychosis without the confounds of substance use, antipsychotic medication use, or illness chronicity.

Association of Hormonal Contraception With Depression
Posted on Monday October 31, 2016

This nationwide cohort study investigates whether the use of hormonal contraception is positively associated with subsequent use of antidepressants and a diagnosis of depression among women in Denmark.


Developed & Designed by Kevin M. Nasky, D.O. • Built with Bootstrap, PHP & MySQL • Hosted by SiteGround
Last updated March 25 2019 15:25:58. Disclaimer: This website does not provide medical advice, nor is it a substitute for clinical judgment.